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10.1038/nrendo.2016.153 25 NomiyamaT.KawanamiT.IrieS.HamaguchiY.TerawakiY.MuraseK.et al (2014)

At 0.25mg per week, a 5mg vial theoretically contains 20 doses, but you can only use it for 4 weeks (28 days) after reconstitution

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Mucosal drug delivery is confronted with the prevalent challenge of insufficient bioavailability in clinical research